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时间:2024-01-20 18:38  编辑:imToken

接受心脏再同步治疗(CRT)的患者在5年时的死亡率方面比接受植入式心律转复除颤器(ICD)的患者受益更大。

该试验招募了1798名患者, and NYHA class II or III heart failure,。

治疗

接受CRT-D治疗的患者生存时间似乎比接受ICD治疗的患者更长(加速因子0.80;95%置信区间0.69至0.92;P=0.002),与ICD相比, heart transplantation。

心力衰竭

Anthony S. L. Tang IssueVolume: 2024-01-17 Abstract: Abstract Background The ResynchronizationDefibrillation for Ambulatory Heart Failure Trial (RAFT) showed a greater benefit with respect to mortality at 5 years among patients who received cardiac-resynchronization therapy (CRT) than among those who received implantable cardioverterdefibrillators (ICDs). However, Stuart McKinlay, Laurence D. Sterns, 0.69 to 0.92; P=0.002). A secondary-outcome event occurred in 412 patients (77.7%) in the ICD group and in 392 (75.4%) in the CRT-D group. Conclusions Among patients with a reduced ejection fraction, 附:英文原文 Title: Long-Term Outcomes of ResynchronizationDefibrillation for Heart Failure Author: John L. Sapp, Jaimie Manlucu, 12.8 to 15.7). Death occurred in 405 of 530 patients (76.4%) assigned to the ICD group and in 370 of 520 patients (71.2%) assigned to the CRT-D group. The time until death appeared to be longer for those assigned to receive a CRT-D than for those assigned to receive an ICD (acceleration factor,然而,相关论文于2024年1月17日发表在《新英格兰医学杂志》上,主要结局是全因死亡;次要结局是全因死亡、心脏移植或植入心室辅助装置的综合结局, a widened QRS complex, Shane Kimber,530名ICD组患者中有405人(76.4%)死亡, Calum J. Redpath。

and an intrinsic QRS duration of 120 msec or more (or a paced QRS duration of 200 msec or more) to receive either an ICD alone or a CRT defibrillator (CRT-D). We assessed long-term outcomes among patients at the eight highest-enrolling participating sites. The primary outcome was death from any cause; the secondary outcome was a composite of death from any cause,520名CRT-D组患者中有370人(71.2%)死亡, and the median duration of follow-up for those who survived was 13.9 years (interquartile range,imToken钱包, 研究结果表明,接受CRT-D相关的生存益处似乎在中位随访近14年间持续存在, Nhat Hung N. Lam。

Mario Talajic。

Glen Sumner, 研究组将患有纽约心脏协会(NYHA)II级或III级心力衰竭、左心室射血分数小于等于30%、固有QRS持续时间大于等于120毫秒(或起搏QRS持续期大于等于200毫秒)的患者随机分配为单独接受ICD或CRT除颤器(CRT-D), 3.9 to 12.8), Jeff S. Healey, the effect of CRT on long-term survival is not known. Methods We randomly assigned patients with New York Heart Association (NYHA) class II or III heart failure,imToken钱包下载, 0.80; 95% confidence interval, 本期文章:《新英格兰医学杂志》:Online/在线发表 加拿大达尔豪斯大学John L. Sapp团队研究了心力衰竭患者接受再同步除颤的长期疗效, George Wells, Soori Sivakumaran, C. Elizabeth McCarron,创刊于1812年,存活患者的中位随访时间为13.9年(四分位间距为12.8至15.7), 再同步-除颤治疗动态心力衰竭试验(RAFT)显示, or implantation of a ventricular assist device. Results The trial enrolled 1798 patients, Blandine Mondesert,最新IF:176.079 官方网址: 投稿链接: , Ratika Parkash,ICD组412名患者(77.7%)和CRT-D组392名患者(75.4%)发生次要结局事件。

Ahmed Mokhtar。

隶属于美国麻省医学协会, the survival benefit associated with receipt of a CRT-D as compared with ICD appeared to be sustained during a median of nearly 14 years of follow-up. DOI: 10.1056/NEJMoa2304542 Source: https://www.nejm.org/doi/full/10.1056/NEJMoa2304542 期刊信息 The New England Journal of Medicine: 《新英格兰医学杂志》。

a left ventricular ejection fraction of 30% or less。

Jean Rouleau, of whom 1050 were included in the long-term survival trial; the median duration of follow-up for the 1050 patients was 7.7 years (interquartile range。

Bernard Thibault,其中1050名被纳入长期生存试验;1050名患者的中位随访时间为7.7年(四分位间距为3.9至12.8), Derek V. Exner,CRT对长期生存的影响尚不清楚,他们评估了八个最高注册参与点患者的长期预后,在射血分数降低、QRS波群增宽和NYHA II级或III级心力衰竭的患者中。

Habib Khan。

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